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Eprinomectin

CAS No.:123997-26-2
C50H75NO14 (Component B1a)      914.13.
C49H73NO14 (Component B1b)      900.10.
Appearance: White to yellowish crystalline powder
Melting Point:173℃
Introduction:
Eprinomectin is a mixture of eprinomectins B1a and B1b in a 9:1 ratio, produced from a mixture of avermectin B1a and B1b. Eprinomectin is used commercially as a topical endectocide (insecticide, miticide and nematocide) for cattle, including lactating dairy cows. Like all avermectins and milbemycins, eprinomectin acts by binding to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite, mite or insect.
Benefits:
By introduction of -NHCOCH3 group, the ratio of Eprinomectin in milk and blood(K value) significantly changed, for dairy cows, K value is 0.102-0.170, it is far away lower than ivermectin. So Eprinomectin can be used for dairy cows which is during lactation period, but without drug withdrawal time.
Finished product:
IVOMEC EPRINEX ® Pour-On for Beef and Dairy Cattle by Merial
LONGRANGE™ (eprinomectin) by Merial

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